Development Scientist - 18 month fixed term contract - #2159286

Fitabeo Therapeutics is a clinical-stage specialty pharmaceutical company that develops and commercialises innovative medicines focusing on indications where existing treatments are inadequate for the target population to provide better health outcomes. It deploys innovative technologies to develop medicines that are expected to enable decentralised patient care and provide significant healthcare savings.

Our company culture is a progressive one based on respect for diverse opinions. Our values include Enablement, Autonomy, Superpower, Experiment and Audacity. We look up to each of our employees to embody our values and play a prominent role in building the culture.

We are looking for someone with a track record of finding unique and compelling ways to develop medicines to deliver superior health outcomes. Are you enthusiastic about being part of a business that is driven by a strong purpose? Are you a people person with a natural ability to think differently? If so, we'd love to hear from you.

PURPOSE STATEMENT

At Fitabeo Therapeutics, we challenge the status quo in terms of pharmaceuticals, as healthcare costs across the world are expected to grow exponentially due to the growing elderly population and a growing number of invasive treatments. We are driven by the fact that healthcare is delivered more efficiently and at reasonable costs if the medicines are administered through non-invasive routes, resulting in decentralised healthcare and providing patients with autonomy.

OUR VALUES

Autonomy: Each one of us within the organisation has freedom/flexibility as we strive toward enhancing patients’ autonomy and to provide equitable access to medication.

Enablement: We prioritise enabling others within the organisation and contribute towards enabling patients to live healthier lives and healthcare savings.

Superpower: We believe that we all have the superpower to bring innovative medicines that will create a lasting impact and enhance patients’ quality of life.

Experiment: We feel comfortable challenging each other in a friendly and motivating work environment.

Audacity: We think and act boldly and believe in our purpose. Sure, people have failed to fit a square peg in a round hole, but we will still try it.

JOB SPECIFICATION

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DEVELOPMENT SCIENTIST

Reporting to:                     Development Director

Responsible for:                   Product Development, Innovation and Technology

Working closely with:           Development Team

Location:                              Glasgow

Term:                                    18-month fixed-term contract

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Responsibilities

·       Raw materials identification and characterisation using appropriate techniques

·       Pre-formulation studies including solubility, compatibility, solid state analysis, in-vitro dissolution, and stability studies (iterative as well as ICH conditions)

·       Designing formulation/process development and analytical testing (based on QbD from project initiation to the target goal or commercialization.

·       In vitro permeation studies (using Franz cells)

·       Writing product development reports and technical reports/summaries independently, including but not limited to:

o  Generating accurate, reliable data by following established procedures and practices for product development; recording, tabulating, summarising and reporting results

o  Interpreting and displaying data clearly and concisely, thoroughly and accurately documenting all formulation and development work

·       Support team/technicians in the design and execution of various product development activities

·       Support in expanding formulation R&D, and analytical capabilities

·       Develop SOPs and technical documents to support IQ/OQ/PQ of equipment

·       Providing technical support for the successful scale-up/Tech. Transfer to the filing of an NDA

·       Interfacing with collaborators and key partners, including but not limited to R&D, CMC, and Regulatory Affairs experts

Requirements

Essential:

·       Minimum education: M Sc/M.Pharm in Chemistry or Pharmaceutical Sciences and PhD in Pharmaceutical Technology/Drug Delivery or related fields

·       3-5 years of experience in oral pharmaceuticals - solid, semi-solid, and liquid product development and testing

·       Ability to work on multiple projects at the same time

·       Ability to interact effectively with peers and work in a fast-paced environment

Desirable:

·       Working experience in the development of oral thin films or transdermal patches

·       GLP and GMP compliance

·       Knowledge of marketing authorisation applications to MHRA and/or FDA